Office of Engineering Safety Texas Engineering Experiment Station TEES The Dwight Look College of Engineering

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2. Key Concepts. Unsafe Biological Substances (Biohazards)Bloodborne PathogensUniversal PrecautionsExposure Control PlanBiosafety in Microbiological and Biomedical Laboratories (BMBL)Biological Risk AssessmentBioSafety Level (BSL)CriteriaBioSecurity CriteriaSelect Agents

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Natural Safety: Safety for individuals, creatures, plants BioSafety and BioHazard Training Office of Engineering Safety Texas Engineering Experiment Station (TEES) & The Dwight Look College of Engineering "A sheltered, fortifying, and secure condition for grant and research."

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Key Concepts Hazardous Biological Substances (Biohazards) Bloodborne Pathogens Universal Precautions Exposure Control Plan Biosafety in Microbiological and Biomedical Laboratories (BMBL) Biological Risk Assessment BioSafety Level (BSL)Criteria BioSecurity Criteria Select Agents & Toxins BioHazard Containment, Decontamination & Disinfection TAMU Biological Safety Office

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Why Is Biological Safety Important? Utilization of perilous natural materials on grounds including Biohazardous specialists and bloodborne pathogens Bloodborne Pathogens Prevent infection in work force Prevent arrival of life forms/operators into condition

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What are BioHazardous Materials? Any natural material equipped for making hurt people, creatures, plants BioHazardous Agents – Pathogens that can imitate & cause infection include: Bacteria ( Streptococcus pyogenes ) Fungi ( Candida, Histoplasma ) Viruses (HIV, HBV) Prions (CJD) Parasites ( Giardia, Strongyloides ) Toxins – Microbial toxic substances Exotoxins – delivered by microscopic organisms Clostridium botulinum - nourishment harming, one of most destructive Clostridium tetanii – lockjaw Corynebacterium diphtheriae – diptheria Bioterrorism utilize Endotoxins – discharged from cell divider when microorganisms disintegrates

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Classification System For Biohazardous Materials BioSafety Levels (BSL)

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The Standard Code of Practice for Biosafety in Microbiological and Biomedical Laboratories (BMBL) U.S. Bureau of Health & Human Services Public Health Service Centers for Disease Control & Prevention & the National Institutes of Health http://www.cdc.gov/od/ohs/biosfty/bmbl5/bmbl5toc.htm Establishes criteria for: Biological Risk Assessment Principles of BioSafety Laboratory BioSafety Level (BSL) Criteria Laboratory BioSecurity Criteria BioHazard Containment Decontamination & Disinfection Transportation of BioHazards & Infectious Materials Select Agents & Toxins…

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Researcher Responsibilities: Faculty or Principle Investigator (PI) Files a Biological Usage Authorization (BUA) Trains all work force Establishes crisis methodology Reports episodes with biologicals Posts biohazard cautioning signs Cooperates with Biological Safety Officer amid review visits Responsibilities of TAMU PI's http://researchcompliance.tamu.edu/ibc/ibcpiresp

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BioSafety Officer TAMU Office of Research Compliance Dr. Bruce M. Whitney Institutional Biological Safety Officer Office of Biological Safety Texas A&M University Tel: 979-458-0683 or 436-1307 Mailstop: 1112 TAMU Email: brucewhitney@tamu.edu Email: bwhitney@vprmail.tamu.edu http://biosafety.tamu.edu/institutional-biosafety-board of trustees/ibcrevapp/ibcapprev

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Institutional BioSafety Committee (IBC) TAMU Office of Research Compliance Mandated by National Institutes of Heath (NIH) Must survey and favor all utilization of Risk Group 2 or higher operators Must audit and endorse rDNA use, development of transgenic creatures, tests including human quality treatment Applies to TAMU: Employees & understudies leading exploration including irresistible biohazrds Research subjects, human or creature TAMU IBC: http://researchcompliance.tamu.edu/ibc/welcome http://biosafety.tamu.edu/institutional-biosafety-council/ibcrevapp/ibcapprev

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Biological Usage Authorization (BUA) Describes the Principle Investigator's Research Project Required when biohazardous material is put away, utilized, or transported Good for a long time Can be altered

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Cannot be brought on grounds! Mycobacterium tuberculosis Hantavirus Foreign Animal Pathogens HIV 1 & 2 Reference material can be kept in dormant state (solidified or lyophilized) List of all references must be given to IBC Forbidden Agents

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CDC Select Agents Cannot be brought on grounds without earlier endorsement & enlistment Must be enrolled with the University BioSafety Officer Required under: U.S. BioTerrorism Prevention Act USA Patriot Act (USAPA) TAMUS Regulations, TEES & TAMU Rules

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The BioSafety Inspection! Individual Protective Equipment Training Signage Adherence to Protocol Technique Physical Facility General Safety Risk Assessment Controls Project Safety Analysis (PSA)

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What You Must Learn to Work Safely with Bloodborne Pathogens Cleaning Decontamination Regulated waste disposal Pre and post presentation strategies Universal Precautions (CDC) Special perils HIV, HBV examine

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What are Bloodborne Pathogens? Microbial operators transmitted by the blood and natural liquids of contaminated people. Control of Occupational Exposures to Bloodborne Pathogens 29 CFR 1910.1030 http://www.osha.gov/SLTC/bloodbornepathogens/index.html

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Exposure Control Plan All research center bosses, workforce & standard examiners are in charge of guaranteeing their representatives and understudies agree to the Exposure Control Plan to decrease the danger of word related exposures to bloodborne pathogens. All faculty that can possibly be presented to bloodborne pathogens MUST be prepared to this arrangement. A duplicate of the Exposure Control Plan must be promptly accessible in each work region or research facility where bloodborne pathogens exposures exist.

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Where to Get More Information www.osha.gov/SLTC/bloodbornepathogens/index.html Workers in various occupations are at danger of presentation to bloodborne pathogens, including Hepatitis B, Hepatitis C, and HIV/AIDS. In 1991, OSHA issued the Bloodborne Pathogens Standard to shield laborers from this hazard. In 2001, in light of the Needlestick Safety and Prevention Act, OSHA overhauled the Bloodborne Pathogens Standard, 29 CFR 1910.1030. The reexamined standard illuminates the requirement for bosses to choose more secure needle gadgets and to include representatives in recognizing and picking these gadgets. The redesigned standard additionally obliges bosses to keep up a log of wounds from debased sharps.

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Where to Get More Training labsafety.tamu.edu/bloodborne.asp Prevention of Exposures to Bloodborne Pathogens (BBP): Exposure to human blood and natural liquids can bring about transmission of a few bloodborne ailments, including HIV and Hepatitis B. This preparation introduction will help in expanding consciousness of the danger of presentation to bloodborne pathogens and methods and practices for anticipating introduction and lessening risks in Engineering research centers and offices.

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Prepared by: http://engineering.tamu.edu/wellbeing/

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Biological Safety: Safety for individuals, creatures, plants BioSafety and BioHazard Training Office of Engineering Safety Texas Engineering Experiment Station (TEES) & The Dwight Look College of Engineering "A sheltered, empowering, and secure condition for grant and research."

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