Slide 2Neuroimaging investigations of ordinary maturing • The impacts of typical maturing on discernment • Neuroimaging as a logical device • The physiological premise of intellectual changes in typical aging
Slide 3Visuospatial aptitudes Attention Executive capacity Language Memory
Slide 4Working Memory is the capacity to keep up and control data over brief timeframes important to guide conduct
Slide 54371506 - > 4371506 MAINTAIN 4371506 - > 6051734 MAINTAIN and MANIPULATE
Slide 6Where's the banner? Would it be advisable for me to kick it? Is this expected to be enjoyable?
Slide 71000 800 20s-30s 50s-60s Mean Reaction Time (msec) 600 70s-80s 400 200 ALONE COUNTING DIGIT SPAN Task Condition
Slide 9STRUCTURAL FUNCTIONAL Magnetic Resonance Imaging Positron Emission Tomography
Slide 10Structural mind changes with maturing changes in cerebrum volume youthful old
Slide 11OTHER BRAIN REGIONS FRONTAL
Slide 12STRUCTURAL FUNCTIONAL Magnetic Resonance Imaging Positron Emission Tomography
Slide 13YOUNG OLD
Slide 17SPATIAL RESOLUTION Primary visual cortex (V1) Ocular strength sections red = right eye blue = left eye
Slide 18TEMPORAL RESOLUTION
Slide 20CUE DELAY RESPONSE +
Slide 22YOUNG ELDERLY UNDER RECRUITMENT NON-SELECTIVE RECRUITMENT OVER RECRUITMENT YOUNG OLD
Slide 24800 600 400 Reaction Time (msec) 200 0 2 Letters 6 Letters
Slide 25FASTEST SLOWEST YOUNG
Slide 26Neural enrollment LESS - - > MORE FAST - - > SLOW Information preparing speed
Slide 271500 1250 1000 750 500 Old Young Reaction Time (msec) 2 6 2 6 Memory Load
Slide 28FASTEST SLOWEST YOUNG OLD
Slide 29Neural enlistment LESS - - - > MORE FAST - - > SLOW YOUNG OLD SLOW - - > FAST Information handling speed
Slide 31Summary • Age-related decrease in particular intellectual procedures • Functional MRI is an effective technique with astounding spatial and worldly determination to concentrate the physiological premise of cognitive decrease in ordinary maturing • Evidence for specific prefrontal cortical brokenness (I.e. under-enlistment) with typical maturing • Possible neural and in addition behavioral remuneration
Slide 33Working memory undertaking Functional MRI EVXRC e time
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