Medications Affecting the Parasympathetic Nervous System

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´╗┐Drugs Affecting the Parasympathetic Nervous System

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Drugs Affecting the Parasympathetic Nervous System Parasympathetic Nervous System Neurotransmitter is ACH The receptors are called cholinergic receptors. Drugs that dilemma to cholinergic receptors and created impacts like ACH are alluded to as cholinergic medications.

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Drugs Affecting the Parasympathetic Nervous System ACH Acetylcholinesterase

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Drugs Affecting the Parasympathetic Nervous System Receptors Muscarinic Receptors Nicotinic Receptors N-1 N-2

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Drugs Affecting the Parasympathetic Nervous System Nicotinic Receptors Nicotinic-II Receptors Nicotinic-I Receptors Found at ganglions of Sympathetic and Parasympathetic Post-ganglionic filaments Found at Neuromuscular intersection of Skeletal muscles.

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Drugs Affecting the Parasympathetic Nervous System Ganglion, Nicotinic I receptor Sympathetic Fibers Post-ganglionic Fiber Pre-ganglionic Fiber Adrenergic Receptor Ganglion, Nicotinic I receptor Parasympathetic Fibers Pre-ganglionic Fiber Post-ganglionic Fiber Muscarinic Receptors Somatic Fibers Nicotinic II Receptors

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Drugs Affecting the Parasympathetic Nervous System Nicotine Alkaloid got from tobacco. Empower the NI receptors at low measurements. Hinder the NII receptors at high measurements.

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Drugs Affecting the Parasympathetic Nervous System Nicotinic I Drugs Ganglionic Stimulants Ganglionic Blockers

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Drugs Affecting the Parasympathetic Nervous System Muscarinic Receptors Found at the parasympathetic postganglionic nerve endings Drugs that demonstration like ACH at these receptors are alluded to as cholinergic or muscarinic drugs. Drugs that square ACH at the muscarinic receptors are alluded to as anticholinergic or antimuscarinic drugs.

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Drugs Affecting the Parasympathetic Nervous System Parasympathetic Drugs Cholinergic Drugs Anti-cholinergic Drugs

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Drugs Affecting the Parasympathetic Nervous System Cholinergic Drugs Direct Acting Cholinergic Drugs Indirect Acting Cholinergic Drugs

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Drugs Affecting the Parasympathetic Nervous System Direct Acting Cholinergic Drugs Bind to muscarinic receptors. Produces ACH like impact. Gradually inactivated by acetylcholinesterase.

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Drugs Affecting the Parasympathetic Nervous System Pharmocological Effects Increase GI discharge and motility Increase in genitourinary movement. Bronchoconstriction

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Drugs Affecting the Parasympathetic Nervous System Pharmocological Effects Miosis Vasodilatation (bring down BP) Decrease heart rate.

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Drugs Affecting the Parasympathetic Nervous System

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Drugs Affecting the Parasympathetic Nervous System Indirect Acting Cholinergic Drugs (Anticholinesterases) Irreversible Inhibitors Reversible Inhibitors

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Drugs Affecting the Parasympathetic Nervous System ACH Acetylcholinesterase Anticholinesterases

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Drugs Affecting the Parasympathetic Nervous System Reversible Inhibitors Blocks cholinergic and nicotinic receptors. Use in the finding and treatment of myasthenia gravis.

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Drugs Affecting the Parasympathetic Nervous System Irreversible Inhibitors Derivatives of organophosphate mixes. Generally utilized as bug sprays, pesticides and concoction fighting operators. Long span of activity

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Drugs Affecting the Parasympathetic Nervous System Clinical Use Topical use in glaucoma Treatment of myasthenia gravis Treatment of urinary maintenance and intestinal stasis

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Drugs Affecting the Parasympathetic Nervous System Clinical Use Treatment of Alzheimer's infection. Antitoxin to skeletal muscle blockers. Counteractants to anticholinergic medication harming.

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Drugs Affecting the Parasympathetic Nervous System Indirect-Acting Cholinergic Drug Irreversible Isoflurophate Reversible Ambenonium Edrophonium Neostigmine Physostigmine Pyridostigmine

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Drugs Affecting the Parasympathetic Nervous System Adverse and Toxic Effect Nausea Vomiting Diarrhea Blurred vision

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Drugs Affecting the Parasympathetic Nervous System Adverse and Toxic Effect Excessive sweating Muscular tremors Bronchoconstriction Bradycardia

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Drugs Affecting the Parasympathetic Nervous System Adverse and Toxic Effect Hypotension Mucular loss of motion Respiratory capture

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Drugs Affecting the Parasympathetic Nervous System Cholinergic Crisis Excessive medication measurements in patients with myasthenia gravis. High convergence of ACH causes exorbitant incitement of the muscarinic receptors. High grouping of ACH causes bar of nicotinic receptor.

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Drugs Affecting the Parasympathetic Nervous System Treatment Stop anticholinesterase sedate organization. Offer atropine to obstruct the impact of abundance muscarinic incitement

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Drugs Affecting the Parasympathetic Nervous System Cholinergic Crisis Excessive presentation to splashes containing subsidiaries of irreversible anticholinesterase. High centralization of ACH causes extreme incitement of the muscarinic receptors. High centralization of ACH causes barricade of nicotinic receptor.

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Drugs Affecting the Parasympathetic Nervous System Treatment Remove individual from the introduction. Offer Pralidoxime to reactivate the anticholinesterase chemical. Offer atropine to hinder the impact of abundance muscarinic incitement

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Drugs Affecting the Parasympathetic Nervous System Anticholinergic Drugs Binds to muscarinic receptors. Act by aggressive enmity of ACH. Model medications: Belladonna alkaloids, atropine and scopolamine

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Drugs Affecting the Parasympathetic Nervous System Pharmacological Action Increase heart rate. Increment the emissions of the respiratory tract and may bring about bronchoconstriction. Lessen salivary and GI tract. Repress urinary peristalsis and voiding of pee.

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Drugs Affecting the Parasympathetic Nervous System Pharmacological Action Depressant impacts on the CNS bringing on sluggishness and sedation. At high measurements cause both incitement and discouragement of the CNS At dangerous dosages excitation, daze, visualization and significant CNS gloom prompting to respiratory capture and passing.

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Drugs Affecting the Parasympathetic Nervous System Ocular Effect Mydriasis Cycloplegia Increases Intraocular weight.

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Drugs Affecting the Parasympathetic Nervous System Adverse and Toxic Effect Cause by unreasonable blockage of the Parasympathetic Nervous System. Dry mouth. Visual unsettling influences Urinary maintenance Constipation.

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Drugs Affecting the Parasympathetic Nervous System Adverse and Toxic Effect Dryness of the skin Flushing Hyperpyrexia CNS incitement and wretchedness

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Drugs Affecting the Parasympathetic Nervous System Anticholinergic Drugs Semisynthetic Drug Homatropine Synthetic Drugs Diclyclomine Isopropamide Propantheline Methantheline Belladonna Alkaloids Atropine Scopolamine Hyoscyamine

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